--- a/virtualization/univention-virtual-machine-manager-daemon/src/univention/uvmm/node.py	
+++ a/virtualization/univention-virtual-machine-manager-daemon/src/univention/uvmm/node.py	
@@ -39,6 +39,7 @@ import libvirt
 import time
 import logging
 import math
+from uuid import UUID
 from .helpers import TranslatableException, ms, tuple2version, N_ as _, uri_encode, FQDN
 from .uvmm_ldap import ldap_annotation, LdapError, LdapConnectionError, ldap_modify
 import univention.admin.uexceptions
@@ -1747,6 +1748,10 @@ def domain_migrate(source_uri, domain, target_uri):
 				time.sleep(1)
 		target_node = node_query(target_uri)
 		target_conn = target_node.conn
+		target_sysinfo = ET.fromstring(target_conn.getSysinfo())
+		target_uuid = UUID(target_sysinfo.find("system/entry[@name='uuid']").text)
+		if target_uuid == UUID(domain):
+			raise NodeError('Migration into self detected: ABORT')
 
 		if source_conn is None:  # offline node
 			domStat = source_node.domains[domain]